Human skin is a multi-layered tissue, with each layer having a unique composition and function. Prolonged loading of the skin, and subcutaneous tissues, can result in the development of pressure ulcers (PUs). Both the mechanical and biochemical responses of human skin are important for different purposes, ranging from the development of shaving appliances, to the prevention of PUs, their early detection and risk assessment. The aim of this thesis was therefore to characterise the mechanical and biochemical response of human skin to diverse loading conditions
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