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Assessing Brain Structure and Function with Diffusion-Weighted MRI: Application to Stroke - Lena Filatova

Human brain consists of grey and white matter. Grey matter largely forms the outer layer of the brain, and is responsible for decision making and functioning of the human body. Complementary, the white matter (WM) contains the communication pathways between the grey matter areas. Diffusion-weighted magnetic resonance imaging (dMRI) is an imaging modality allowing to model the brain’s white matter structures by making the MRI acquisition sensitive to diffusion processes. When brain structure is altered due to pathology, it can be assessed and quantified by analysing dMRI data. This thesis investigates the influence of stroke on the brain’s white matter structure based on dMRI-measurements and functional properties measured with EEG. This work is part of the 4D EEG project, one of the aims of which was to evaluate outcomes of the stroke patients in terms of their WM integrity and brain function.

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